Sheffield United were relegated from the Premier League after surrendering an early lead to suffer a 5-1 thrashing at Newcastle.
Anel Ahmedhodzic’s fifth-minute opener at St James’ Park gave the beleaguered Blades hope of earning a stay of execution.
But Alexander Isak’s second-half brace, plus finishes from Bruno Guimaraes and Callum Wilson either side of a Ben Osborn own goal, inflicted a 25th defeat of a miserable season on the South Yorkshire club to boost the Magpies’ hopes of Europa League qualification.
Manchester United’s disappointing season continued after Zeki Amdouni’s late penalty earned relegation-threatened Burnley a 1-1 draw at Old Trafford.
The result moved Burnley two points from safety, while fellow strugglers Luton remain a single point behind 17th-placed Nottingham Forest following a 2-1 loss at Wolves.
Goals in either half from Hwang Hee-chan and Toti Gomes put the hosts in control before Carlton Morris’ 10th league strike of the campaign set up a tense finale.
Everton banished any lingering relegation fears by building on their Merseyside derby success over Liverpool with a 1-0 victory against Brentford at Goodison Park.
Idrissa Gueye’s powerful second-half finish earned the Toffees a third successive win – and a fourth in five games – to lift them above the Bees and 11 points clear of the drop zone.
At Craven Cottage, Jeffrey Schlupp scored a stunning late leveller as Crystal Palace grabbed a 1-1 draw against London rivals Fulham.
Substitute Schlupp rifled home three minutes from time to cancel out Rodrigo Muniz’s 52nd-minute opener and maintain Palace’s impressive form under Oliver Glasner following three successive wins.